Phu posted a good movie suggestion "Event Horizon" which went along with Toneguns' idea of finding a lost spaceship. You could do something like that and it could be all creepy when they find the lost spaceship and its been infected with something. For some reason that theme always gives me the willies even though its one of the more unlikely things to happen in my lifetime.

Otherwise maybe jump in time a couple hundred years and do something more along the lines of the Fifth Element which had the cool concept of a powerful Earth empire fighting against different rogue elements that didn't want to be a part of it.

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